Escape into the island mindset at Hyatt Place Manatí, a modern hotel with tropical flair along the north shore of Puerto Rico. El Trigal Plaza mall is a five-minute walk across the street, and our central location allows guests to decide their day on a whim. Hyatt Place is a different kind of hotel designed around our guests. We are located off exit 48 on Jose de Diego Expressway PR-22, at the intersection of PR-149 and PR-2. We are minutes from top medical facilities and growing medical tourism district as well as shopping and dining options.