Río Espíritu Santo Address Río Espíritu Santo Río Espíritu Santo Río Grande, PR, 00745 Contact View on a Map Get Directions 1 / 7 About The Río Espíritu Santo in Río Grande starts high up in the mountains of El Yunque Rainforest. If you include Río Espíritu Santo in your itinerary, you can enjoy a leisurely boat ride along the river bend or you can choose to go chasing waterfalls. Videos & 360° Tours Amenities Payment Methods Accepted Meetings Facilities Meeting Rooms sq. ft.Largest Room Sleeping Rooms sq. ft.Meeting Space Download Floorplan Event Spaces / Meeting Rooms Room Sq. Ft. Theater Classroom Banquet Reception Deals